Quick Note: This is general information, not medical advice. Always talk to your prescriber or healthcare professional about any treatment decisions or concerns about stopping.

The Part No One Likes to Talk About

Let’s get this out of the way first: a little weight gain is always expected when you stop.

It happens to everyone.

You’ve taken away the appetite suppression, the food noise might come back, and your body is naturally going to test the waters to see what it can get away with.

That doesn’t mean you're destined for failure.

The important thing is recognising it early and keeping it in check, so that a couple of pounds or kilos doesn’t snowball into something that feels unmanageable again.

Think of it as the learning phase. This is when you go from letting the pen make decisions for you to doing the work yourself.

Yes, the pen did it for you. It helped you reach your goal. But do you really want to let go of that now?

The medication might have done the heavy lifting, but it was still you. You chose smaller portions. You said no to cravings. You let yourself feel full and stop. That wasn’t cheating. It wasn’t skipping the hard part. It was still hard work.

Don’t let go of that now.

Why Does Regain Happen?

Weight regain after stopping a GLP-1 isn’t about willpower or personal failure. It’s about biology and behaviour.

When you’re on Mounjaro, Ozempic, or Wegovy, appetite signals are turned way down. Food noise is quiet. You’re not fighting cravings all day, and when you stop? Those signals can come back.

Your body might defend its old “set point”, the weight it thinks is normal for you. Hunger might feel sharper. Portions might creep back up. Food choices might slide into old habits.

It’s not about blame. It’s about understanding what’s happening so you can plan for it.